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"Whereas cells from younger donors were highly selective in the odorants to which they responded, cells from older donors were more likely to respond to multiple odor stimuli� suggesting a loss of specificity. The study suggests that changes in nose and the brain contribute to smell loss in the elderly."
In a study of mice reported in 2014 in the Journal of Neuroscience, Florida State University post-doctoral researcher Nicolas Thiebaud and colleagues showed a reverse link: that a bad diet impacted on the sense of smell. When mice were given a high-fat diet over a period of six months showed a significant reduction in their ability to distinguish odours.
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